Everywhere you look, there are ads for new workouts, diet strategies, and weight loss supplements. It is for good reason – more than one third of American adults are overweight. If you are expecting to lose several pounds, though, the barrage of choices can be daunting, and it may be hard to select the one that is best. In a new study. researchers from the University of California, San Diego examined the five pharmacological alternatives that are approved for handling obesity in America. They all are weight loss tablets that work, but the research found some are far better than others.
The details of the study about weight loss tablets that work
The study involved more than 29,000 people, and suggested Qsymia (phentermine-topiramate) and Victoza (liraglutide) gave patients the highest chance of shedding at least 5 percent of their body weight. Xenical was the least successful. But according to Dr. Siddarth Singh, the study’s lead researcher, there’s no single drug that is best for everyone.
“Obesity treatment constantly must be personalized,” he said in a press release. He added the study merely supplies averages. And that side effects are an important part of treatment that should be contemplated.
Singh’s team analyzed the effects of 28 clinical trials that analyzed the five drugs: Qsymia, Victoza, Xenical, Belviq (lorcaserin) and Contrave (naltrexone-bupropion). They found that on average, each drug worked better than a placebo. But Qsymia is the weight loss tablets that work the best. Folks on it generally lost the most weight. These patients shed almost 20 more pounds than those given a placebo, while patients taking Xenical or Belviq tended to lose the least amount of weight – about 6 to 7 pounds more than placebo users.
Can pills actually make you shed weight?
Though some of the drugs were mostly successful, they did not work for everyone. This was because people respond differently to different weight loss drugs, said Nikhil Dhurandhar, a spokesman for the Obesity Society, in the press release.
“In general, if you give drug ‘X,’ there will be a broad variation in patients’ reactions,” Dhurandhar said, adding that some of US will observe the pounds slide off but others WOn’t lose any at all. He said there’s no such thing as a magic pill that can melt down fat. “These drugs can allow you to eat less through effects on desire, but you’ve got to alter your diet and get regular exercise. Drugs, even weight loss drugs that work, are nutritional supplements, not replacements, to your attempts.”
When it comes to unintended health consequences, Contrave and Victoza were the least successful drugs. Patients who took these medicines nearly three times more likely to stop the trial due to side effects.
What’s the conclusion?
Singh reiterated that because weight loss drugs affect everyone differently, that also means they’ll face individual risks for side effects.
Contrave, for example, includes the antidepressant bupropion and includes a warning about suicidal ideas. Because of this, a man with mental illness or psychiatric symptoms may be better off selecting an alternate obesity drug. Another one of the drugs, Victoza, is effective at causing kidney problems and inflammation of the pancreas.
Weight loss tablets that really work are definitely an important alternative for handling obesity. But most weight loss drugs have just been approved within the last couple years, according to Singh. This means we aren’t yet certain if their effects will endure over the long run.